Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients

BACKGROUND: Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by transforming growth factor-beta (TGFβ). However, the...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Takano, Shotaro, Uchida, Kentaro, Shoji, Shintaro, Itakura, Makoto, Iwase, Dai, Aikawa, Jun, Mukai, Manabu, Sekiguchi, Hiroyuki, Inoue, Gen, Takaso, Masashi
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791277/
https://ncbi.nlm.nih.gov/pubmed/31662989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6959056
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