Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis

BACKGROUND: The infrapatellar fat pad (IFP) is implicated in knee osteoarthritis (KOA). Calcitonin gene-related peptide (CGRP), a vasoactive neuropeptide expressed in joint tissues and synovial tissues (ST), was recently found to be associated with KOA progression and pain. CGRP is expressed in the...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Aikawa, Jun, Uchida, Kentaro, Takano, Shotaro, Inoue, Gen, Iwase, Dai, Miyagi, Masayuki, Mukai, Manabu, Shoji, Shintaro, Sekiguchi, Hiroyuki, Takaso, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134514/
https://ncbi.nlm.nih.gov/pubmed/30205824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0864-8
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