Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia

BACKGROUND: While epidemiological studies have reported a potential role for hypercholesterolemia (HCE) in osteoarthritis (OA), the association between HCE and OA has yet to be clarified. Adipose tissue is a primary locus for cholesterol metabolism and the presence of HCE reportedly causes adipose d...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Mukai, Manabu, Uchida, Kentaro, Takano, Shotaro, Iwase, Dai, Aikawa, Jun, Inoue, Gen, Miyagi, Masayuki, Takaso, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001124/
https://ncbi.nlm.nih.gov/pubmed/29898737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0792-7
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