Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production

BACKGROUND: Inflammation-induced dysfunction of hepatic stellate cells (HSCs) is involved in schistosomiasis-associated liver fibrosis, and soluble egg antigen (SEA) is a crucial pathogen-associated molecular pattern associated with liver injury in schistosomiasis. In addition, numerous studies have...

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Dettagli Bibliografici
Pubblicato in:Parasit Vectors
Autori principali: Kong, De-Long, Kong, Fan-Yun, Liu, Xiang-Ye, Yan, Chao, Cui, Jie, Tang, Ren-Xian, Zheng, Kui-Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791022/
https://ncbi.nlm.nih.gov/pubmed/31610797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3729-8
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