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Adaptive mechanisms driving maladaptive pain: how chronic ongoing activity in primary nociceptors can enhance evolutionary fitness after severe injury

Chronic pain is considered maladaptive by clinicians because it provides no apparent protective or recuperative benefits. Similarly, evolutionary speculations have assumed that chronic pain represents maladaptive or evolutionarily neutral dysregulation of acute pain mechanisms. By contrast, the pres...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Autor principal: Walters, Edgar T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790390/
https://ncbi.nlm.nih.gov/pubmed/31544606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0277
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