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Nociceptors as chronic drivers of pain and hyperreflexia after spinal cord injury: an adaptive-maladaptive hyperfunctional state hypothesis
Spinal cord injury (SCI) causes chronic peripheral sensitization of nociceptors and persistent generation of spontaneous action potentials (SA) in peripheral branches and the somata of hyperexcitable nociceptors within dorsal root ganglia (DRG). Here it is proposed that SCI triggers in numerous noci...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429080/ https://ncbi.nlm.nih.gov/pubmed/22934060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00309 |
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