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Adaptive mechanisms driving maladaptive pain: how chronic ongoing activity in primary nociceptors can enhance evolutionary fitness after severe injury

Chronic pain is considered maladaptive by clinicians because it provides no apparent protective or recuperative benefits. Similarly, evolutionary speculations have assumed that chronic pain represents maladaptive or evolutionarily neutral dysregulation of acute pain mechanisms. By contrast, the pres...

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Pubblicato in:Philos Trans R Soc Lond B Biol Sci
Autore principale: Walters, Edgar T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790390/
https://ncbi.nlm.nih.gov/pubmed/31544606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0277
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