Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling

BACKGROUND: A single dose of IV fish oil (FO) before hepatic ischemia reperfusion injury (HIRI) increases hepatocyte proliferation and reduces necrosis in wild type (WT) mice. It has been suggested that the GPR120 receptor on Kupffer cells mediates FO’s ability to reduce HIRI. The purpose of this st...

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Udgivet i:J Pediatr Surg
Main Authors: Baker, Meredith A., Nandivada, Prathima, Mitchell, Paul D., Fell, Gillian L., Pan, Amy, Cho, Bennet S., De La Flor, Denis J., Anez-Bustillos, Lorenzo, Dao, Duy T., Nosé, Vania, Puder, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790164/
https://ncbi.nlm.nih.gov/pubmed/31036368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2019.04.003
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