Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma

INTRODUCTION: The epigenetic regulator Bmi1 is essential for the self-renewal of neural stem cells (NSC), and highly expressed in glioblastoma (GBM) stem/initiating cells (GIC), where knockdown significantly reduces tumour growth in xenograft models. We have used a combined genome-wide and target ge...

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I publikationen:Neuro Oncol
Huvudupphovsmän: Oliver Millner, Thomas, Ricci, Barbara, Zhang, Xinyu, Pomella, Nicola, Marino, Silvia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789976/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.004
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