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Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma
INTRODUCTION: The epigenetic regulator Bmi1 is essential for the self-renewal of neural stem cells (NSC), and highly expressed in glioblastoma (GBM) stem/initiating cells (GIC), where knockdown significantly reduces tumour growth in xenograft models. We have used a combined genome-wide and target ge...
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| Publicat a: | Neuro Oncol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6789976/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.004 |
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