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Single-molecule localization microscopy as nonlinear inverse problem

We present a statistical framework to model the spatial distribution of molecules based on a single-molecule localization microscopy (SMLM) dataset. The latter consists of a collection of spatial coordinates and their associated uncertainties. We describe iterative parameter-estimation algorithms ba...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yu, Ji, Elmokadem, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789733/
https://ncbi.nlm.nih.gov/pubmed/31548404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912634116
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