Sinomenine ameliorates intervertebral disc degeneration via inhibition of apoptosis and autophagy in vitro and in vivo

Background: Aberrant apoptosis in nucleus pulposus (NP) cells is the primary cause of intervertebral disc degeneration (IDD). In contrast, a large number of studies have confirmed that autophagy may protect NP cells from apoptosis. Sinomenine is an alkaloid monomer, which has been reported to stimul...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Gao, Zengxin, Lin, Yucheng, Zhang, Pei, Cheng, Qinghua, Ye, Linhui, Wu, Fuhua, Chen, Yingjun, Fu, Minghui, Cheng, Changgui, Gao, Yucheng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789258/
https://ncbi.nlm.nih.gov/pubmed/31632563
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