Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway

Intervertebral disc degeneration (IDD) has been generally accepted as the major cause of low back pain (LBP), which causes an enormous socioeconomic burden. Previous studies demonstrated that the apoptosis of nucleus pulposus (NP) cells and the dyshomeostasis of extracellular matrix (ECM) contribute...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Wang, Dong, He, Xin, Wang, Di, Peng, Pandi, Xu, Xiaolong, Gao, Bo, Zheng, Chao, Wang, Han, Jia, Haoruo, Shang, Qiliang, Sun, Zhen, Luo, Zhuojing, Yang, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758489/
https://ncbi.nlm.nih.gov/pubmed/33363176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.613006
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