Myeloid-derived suppressor cells (MDSCs) and mechanistic target of rapamycin (mTOR) signaling pathway interact through inducible nitric oxide synthase (iNOS) and nitric oxide (NO) in asthma

Background: Down-regulation of mechanistic target of rapamycin (mTOR) activity in myeloid-derived suppressor cells (MDSCs) has been shown to promote inducible nitric oxide (NO) synthase (iNOS) expression and NO production. Importantly, pharmacological inhibition of iNOS blocks MDSCs recruitment in i...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Zhang, Yanli, Xu, Boyi, Luan, Bin, Zhang, Yan, Li, Yanling, Xiong, Xiaorong, Shi, Hongke
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789223/
https://ncbi.nlm.nih.gov/pubmed/31632585
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