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Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses
Cytosolic mitochondrial DNA (mtDNA) activates cGAS-mediated antiviral immune responses, but the mechanism by which RNA viruses stimulate mtDNA release remains unknown. Here we show that viroporin activity of influenza virus M2 or encephalomyocarditis virus (EMCV) 2B protein triggers translocation of...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6789137/ https://ncbi.nlm.nih.gov/pubmed/31604929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12632-5 |
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