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Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection

Nod-like receptor family, pyrin domain-containing 3 (NLRP3), is involved in the early stages of the inflammatory response by sensing cellular damage or distress due to viral or bacterial infection. Activation of NLRP3 triggers its assembly into a multimolecular protein complex, termed “NLRP3 inflamm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ichinohe, Takeshi, Yamazaki, Tatsuya, Koshiba, Takumi, Yanagi, Yusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816452/
https://ncbi.nlm.nih.gov/pubmed/24127597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312571110
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