The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion

Inflammasomes are cytosolic multimolecular protein complexes that stimulate the activation of caspase-1 and the release of mature forms of interleukin-1β (IL-1β) and IL-18. We previously demonstrated that the influenza A virus M2 protein stimulates IL-1β secretion following activation of the nucleot...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Moriyama, Miyu, Chen, I-Yin, Kawaguchi, Atsushi, Koshiba, Takumi, Nagata, Kyosuke, Takeyama, Haruko, Hasegawa, Hideki, Ichinohe, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810543/
https://ncbi.nlm.nih.gov/pubmed/26865721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00120-16
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