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HCMV-encoded US7 and US8 act as antagonists of innate immunity by distinctively targeting TLR-signaling pathways

The mechanisms by which many human cytomegalovirus (HCMV)-encoded proteins help the virus to evade immune surveillance remain poorly understood. In particular, it is unknown whether HCMV proteins arrest Toll-like receptor (TLR) signaling pathways required for antiviral defense. Here, we report that...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Park, Areum, Ra, Eun A., Lee, Taeyun A., Choi, Hyun jin, Lee, Eunhye, Kang, Sujin, Seo, Jun-Young, Lee, Sungwook, Park, Boyoun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789044/
https://ncbi.nlm.nih.gov/pubmed/31604943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12641-4
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