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Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses

Human cytomegalovirus (HCMV) has evolved sophisticated immune evasion mechanisms that target both the innate and adaptive immune responses. However, how HCMV encoded proteins are involved in this immune escape is not clear. Here, we show that HCMV glycoprotein US9 inhibits the IFN-β response by targ...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Choi, Hyun jin, Park, Areum, Kang, Sujin, Lee, Eunhye, Lee, Taeyun A., Ra, Eun A., Lee, Jiseon, Lee, Sungwook, Park, Boyoun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760629/
https://ncbi.nlm.nih.gov/pubmed/29317664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02624-8
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