Llwytho...
Negative Self-Regulation of TLR9 Signaling by Its N-Terminal Proteolytic Cleavage Product
TLR signaling is essential to innate immunity against microbial invaders and must be tightly controlled. We have previously shown that TLR9 undergoes proteolytic cleavage processing by lysosomal proteases to generate two distinct fragments. The C-terminal cleavage product plays a critical role in ac...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Immunol |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285150/ https://ncbi.nlm.nih.gov/pubmed/25187653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400210 |
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