Molecular mechanism of tumour necrosis factor alpha regulates hypocretin (orexin) expression, sleep and behaviour

Hypocretin 1 and hypocretin 2 (orexin A and B) regulate sleep, wakefulness and emotion. Tumour necrosis factor alpha (TNF‐α) is an important neuroinflammation mediator. Here, we examined the effects of TNF‐α treatment on hypocretin expression in vivo and behaviour in mice. TNF‐α decreased hypocretin...

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Publicado en:J Cell Mol Med
Autores principales: Zhan, Shuqin, Che, Pulin, Zhao, Xue‐ke, Li, Ning, Ding, Yan, Liu, Jianghong, Li, Spring, Ding, Karyn, Han, Lynn, Huang, Zhaoyang, Wu, Liyong, Wang, Yuping, Hu, Meng, Han, Xiaosi, Ding, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787512/
https://ncbi.nlm.nih.gov/pubmed/31386303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14566
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