Molecular mechanism of tumour necrosis factor alpha regulates hypocretin (orexin) expression, sleep and behaviour

Hypocretin 1 and hypocretin 2 (orexin A and B) regulate sleep, wakefulness and emotion. Tumour necrosis factor alpha (TNF‐α) is an important neuroinflammation mediator. Here, we examined the effects of TNF‐α treatment on hypocretin expression in vivo and behaviour in mice. TNF‐α decreased hypocretin...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Zhan, Shuqin, Che, Pulin, Zhao, Xue‐ke, Li, Ning, Ding, Yan, Liu, Jianghong, Li, Spring, Ding, Karyn, Han, Lynn, Huang, Zhaoyang, Wu, Liyong, Wang, Yuping, Hu, Meng, Han, Xiaosi, Ding, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787512/
https://ncbi.nlm.nih.gov/pubmed/31386303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14566
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