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DNA sequence-dependent chromatin architecture and nuclear hubs formation
In this study, by exploring chromatin conformation capture data, we show that the nuclear segregation of Topologically Associated Domains (TADs) is contributed by DNA sequence composition. GC-peaks and valleys of TADs strongly influence interchromosomal interactions and chromatin 3D structure. To ga...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6787200/ https://ncbi.nlm.nih.gov/pubmed/31601866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51036-9 |
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