Trace amine-associated receptor gene polymorphism increases drug craving in individuals with methamphetamine dependence

BACKGROUND: Methamphetamine (MA) is a potent agonist at the trace amine-associated receptor 1 (TAAR1). This study evaluated a common variant (CV) in the human TAAR1 gene, synonymous single nucleotide polymorphism (SNP) V288V, to determine the involvement of TAAR1 in MA dependence. METHODS: Participa...

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發表在:PLoS One
Main Authors: Loftis, Jennifer M., Lasarev, Michael, Shi, Xiao, Lapidus, Jodi, Janowsky, Aaron, Hoffman, William F., Huckans, Marilyn
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786581/
https://ncbi.nlm.nih.gov/pubmed/31600226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220270
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