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The Role of Biogenic Amine Transporters in Trace Amine–Associated Receptor 1 Regulation of Methamphetamine-Induced Neurotoxicity

Methamphetamine (MA) impairs vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function and expression, increasing intracellular DA levels that lead to neurotoxicity. The trace amine–associated receptor 1 (TAAR1) is activated by MA, but when the receptor is not activated, MA-i...

詳細記述

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書誌詳細
出版年:J Pharmacol Exp Ther
主要な著者: Miner, Nicholas B., Phillips, Tamara J., Janowsky, Aaron
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750185/
https://ncbi.nlm.nih.gov/pubmed/31320495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258970
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