Trace amine-associated receptor gene polymorphism increases drug craving in individuals with methamphetamine dependence

BACKGROUND: Methamphetamine (MA) is a potent agonist at the trace amine-associated receptor 1 (TAAR1). This study evaluated a common variant (CV) in the human TAAR1 gene, synonymous single nucleotide polymorphism (SNP) V288V, to determine the involvement of TAAR1 in MA dependence. METHODS: Participa...

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Udgivet i:PLoS One
Main Authors: Loftis, Jennifer M., Lasarev, Michael, Shi, Xiao, Lapidus, Jodi, Janowsky, Aaron, Hoffman, William F., Huckans, Marilyn
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786581/
https://ncbi.nlm.nih.gov/pubmed/31600226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220270
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