LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

BACKGROUND: PVT1 has emerged as an oncogene in many tumor types. However, its role in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) is unknown. The aim of this study was to assess the role of PVT1 in BE/EAC progression and uncover its therapeutic value against EAC. METHODS: PVT1 expre...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Xu, Yan, Li, Yuan, Jin, Jiankang, Han, Guangchun, Sun, Chengcao, Pizzi, Melissa Pool, Huo, Longfei, Scott, Ailing, Wang, Ying, Ma, Lang, Lee, Jeffrey H., Bhutani, Manoop S., Weston, Brian, Vellano, Christopher, Yang, Liuqing, Lin, Chunru, Kim, Youngsoo, MacLeod, A. Robert, Wang, Linghua, Wang, Zhenning, Song, Shumei, Ajani, Jaffer A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785865/
https://ncbi.nlm.nih.gov/pubmed/31601234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1064-5
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