The crosstalk between STAT3 and p53/RAS signaling controls cancer cell metastasis and cisplatin resistance via the Slug/MAPK/PI3K/AKT-mediated regulation of EMT and autophagy

Chemoresistance has been the biggest obstacle in ovarian cancer treatment, and STAT3 may play an important role in chemoresistance of multiple cancers, but the underlying mechanism of STAT3 in ovarian cancer chemoresistance has long been truly illusive, particularly in association with p53 and RAS s...

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Publicado en:Oncogenesis
Main Authors: Liang, Fan, Ren, Chunxia, Wang, Jingshu, Wang, Shuoer, Yang, Lina, Han, Xianghui, Chen, Yaping, Tong, Guoqing, Yang, Gong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785561/
https://ncbi.nlm.nih.gov/pubmed/31597912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0165-8
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