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Analysis of “old” proteins unmasks dynamic gradient of cartilage turnover in human limbs

Unlike highly regenerative animals, such as axolotls, humans are believed to be unable to counteract cumulative damage, such as repetitive joint use and injury that lead to the breakdown of cartilage and the development of osteoarthritis. Turnover of insoluble collagen has been suggested to be very...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Hsueh, Ming-Feng, Önnerfjord, Patrik, Bolognesi, Michael P., Easley, Mark E., Kraus, Virginia B.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785252/
https://ncbi.nlm.nih.gov/pubmed/31633025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3203
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