Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method

Fucosylated glycoconjugates are involved in a variety of physiological and pathological processes. However, economical production of fucosylated drugs and prebiotic supplements has been hampered by the poor catalytic efficiency of fucosyltransferases. Here, we developed a fluorescence-activated cell...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Tan, Yumeng, Zhang, Yong, Han, Yunbin, Liu, Hao, Chen, Haifeng, Ma, Fuqiang, Withers, Stephen G., Feng, Yan, Yang, Guangyu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785251/
https://ncbi.nlm.nih.gov/pubmed/31633018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw8451
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