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High-throughput Screening for Inhibitors of Sialyl- and Fucosyltransferases

[Image: see text] Sweet Screens: The promiscuity of sialyl- and fucosyltransferases has been exploited to develop a high-throughput screening (HTS) platform wherein transfer of a fluorescent analog of the natural donor substrate to a glycoprotein acceptor results in a robust fluorescence polarizatio...

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Detalhes bibliográficos
Main Authors: Rillahan, Cory D., Brown, Steven J., Register, Amy C., Rosen, Hugh, Paulson, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245354/
https://ncbi.nlm.nih.gov/pubmed/22095645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201105065
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