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Global Metabolic Inhibitors of Sialyl- and Fucosyltransferases
Despite the fundamental roles of sialyl- and fucosyltransferases in mammalian physiology, there are few pharmacological tools to manipulate their function in a cellular setting. Although fluorinated analogs of the donor substrates are well-established transition state inhibitors of these enzymes, th...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427410/ https://ncbi.nlm.nih.gov/pubmed/22683610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.999 |
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