Global Metabolic Inhibitors of Sialyl- and Fucosyltransferases

Despite the fundamental roles of sialyl- and fucosyltransferases in mammalian physiology, there are few pharmacological tools to manipulate their function in a cellular setting. Although fluorinated analogs of the donor substrates are well-established transition state inhibitors of these enzymes, th...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rillahan, Cory D., Antonopoulos, Aristotelis, Lefort, Craig T., Sonon, Roberto, Azadi, Parastoo, Ley, Klaus, Dell, Anne, Haslam, Stuart M., Paulson, James C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427410/
https://ncbi.nlm.nih.gov/pubmed/22683610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.999
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