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MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure

Understanding tissue structure and function requires tools that quantify the expression of multiple proteins while preserving spatial information. Here, we describe MIBI-TOF (multiplexed ion beam imaging by time of flight), an instrument that uses bright ion sources and orthogonal time-of-flight mas...

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Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Keren, Leeat, Bosse, Marc, Thompson, Steve, Risom, Tyler, Vijayaragavan, Kausalia, McCaffrey, Erin, Marquez, Diana, Angoshtari, Roshan, Greenwald, Noah F., Fienberg, Harris, Wang, Jennifer, Kambham, Neeraja, Kirkwood, David, Nolan, Garry, Montine, Thomas J., Galli, Stephen J., West, Robert, Bendall, Sean C., Angelo, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785247/
https://ncbi.nlm.nih.gov/pubmed/31633026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax5851
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