A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging

The immune system is critical in modulating cancer progression, but knowledge of immune composition, phenotype, and interactions with tumor is limited. We used Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF) to simultaneously quantify in-situ expression of 36 proteins covering identity, fu...

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Veröffentlicht in:Cell
Hauptverfasser: Keren, Leeat, Bosse, Marc, Marquez, Diana, Angoshtari, Roshan, Jain, Samir, Varma, Sushama, Yang, Soo-Ryum, Kurian, Allison, Van Valen, David, West, Robert, Bendall, Sean C, Angelo, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132072/
https://ncbi.nlm.nih.gov/pubmed/30193111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.039
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