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Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments

Recent in situ multiplexed profiling techniques provide insight into microenvironment formation, maintenance, and transformation through a lens of localized cellular phenotype distribution. In this article, we introduce a method for recovering signatures of microenvironments from such data. We use t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Comput Biol
Prif Awduron: Chen, Zhenghao, Soifer, Ilya, Hilton, Hugo, Keren, Leeat, Jojic, Vladimir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc., publishers 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415889/
https://ncbi.nlm.nih.gov/pubmed/32243203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0340
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