A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging

The immune system is critical in modulating cancer progression, but knowledge of immune composition, phenotype, and interactions with tumor is limited. We used Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF) to simultaneously quantify in-situ expression of 36 proteins covering identity, fu...

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Vydáno v:Cell
Hlavní autoři: Keren, Leeat, Bosse, Marc, Marquez, Diana, Angoshtari, Roshan, Jain, Samir, Varma, Sushama, Yang, Soo-Ryum, Kurian, Allison, Van Valen, David, West, Robert, Bendall, Sean C, Angelo, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132072/
https://ncbi.nlm.nih.gov/pubmed/30193111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.039
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