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Non-canonical Wnt signaling orchestrates early developmental events towards mesodermal hematopoietic cell fate from human embryonic stem cells
During human development, signals that govern lineage specification versus expansion of cells committed to a cell fate are poorly understood. We demonstrate that activation of canonical Wnt signaling by Wnt-3a promotes proliferation of human embryonic stem cells (hESCs) -precursors already committed...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742366/ https://ncbi.nlm.nih.gov/pubmed/19265664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.12.011 |
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