Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses

Endocannabinoid signaling via anandamide (AEA) is implicated in a variety of neuronal functions and considered a promising therapeutic target for numerous emotion-related disorders. The major AEA degrading enzyme is fatty acid amide hydrolase (FAAH). Genetic deletion and pharmacological inhibition o...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Zimmermann, Tina, Bartsch, Julia C., Beer, Annika, Lomazzo, Ermelinda, Guggenhuber, Stephan, Lange, Maren D., Bindila, Laura, Pape, Hans-Christian, Lutz, Beat
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784910/
https://ncbi.nlm.nih.gov/pubmed/30532004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0274-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires