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MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors

The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most diagnostic laboratories. Thus, we have proposed a ne...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Viruses
Prif Awduron: Aralaguppe, Shambhu G., Ambikan, Anoop T., Ashokkumar, Manickam, Kumar, Milner M., Hanna, Luke Elizabeth, Amogne, Wondwossen, Sönnerborg, Anders, Neogi, Ujjwal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784143/
https://ncbi.nlm.nih.gov/pubmed/31480341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11090806
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