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MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors

The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most diagnostic laboratories. Thus, we have proposed a ne...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Aralaguppe, Shambhu G., Ambikan, Anoop T., Ashokkumar, Manickam, Kumar, Milner M., Hanna, Luke Elizabeth, Amogne, Wondwossen, Sönnerborg, Anders, Neogi, Ujjwal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784143/
https://ncbi.nlm.nih.gov/pubmed/31480341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11090806
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