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Dynamic Views of the Fc Region of Immunoglobulin G Provided by Experimental and Computational Observations
The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs). These interactions are critically dependent on the pair of N-glycans packed between the two C(H)2 domains. Fucosylation of these N-glycans negati...
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| 出版年: | Antibodies (Basel) |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6784063/ https://ncbi.nlm.nih.gov/pubmed/31544845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8030039 |
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