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A Spectroscopic Study on Secondary Structure and Thermal Unfolding of the Plant Toxin Gelonin Confirms Some Typical Structural Characteristics and Unravels the Sequence of Thermal Unfolding Events

Gelonin from the Indian plant Gelonium multiflorum belongs to the type I ribosome-inactivating proteins (RIPs). Like other members of RIPs, this toxin glycoprotein inhibits protein synthesis of eukaryotic cells; hence, it is largely used in the construction of immunotoxins composed of cell-targeted...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Scirè, Andrea, Tanfani, Fabio, Ausili, Alessio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783991/
https://ncbi.nlm.nih.gov/pubmed/31443430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090483
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