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A Spectroscopic Study on Secondary Structure and Thermal Unfolding of the Plant Toxin Gelonin Confirms Some Typical Structural Characteristics and Unravels the Sequence of Thermal Unfolding Events

Gelonin from the Indian plant Gelonium multiflorum belongs to the type I ribosome-inactivating proteins (RIPs). Like other members of RIPs, this toxin glycoprotein inhibits protein synthesis of eukaryotic cells; hence, it is largely used in the construction of immunotoxins composed of cell-targeted...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Scirè, Andrea, Tanfani, Fabio, Ausili, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783991/
https://ncbi.nlm.nih.gov/pubmed/31443430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090483
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