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A Spectroscopic Study on Secondary Structure and Thermal Unfolding of the Plant Toxin Gelonin Confirms Some Typical Structural Characteristics and Unravels the Sequence of Thermal Unfolding Events

Gelonin from the Indian plant Gelonium multiflorum belongs to the type I ribosome-inactivating proteins (RIPs). Like other members of RIPs, this toxin glycoprotein inhibits protein synthesis of eukaryotic cells; hence, it is largely used in the construction of immunotoxins composed of cell-targeted...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Scirè, Andrea, Tanfani, Fabio, Ausili, Alessio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783991/
https://ncbi.nlm.nih.gov/pubmed/31443430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090483
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