Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition

Ribosome-synthesized post-translationally modified peptides (RiPPs) represent a rapidly expanding class of natural products with various biological activities. Linear azol(in)e-containing peptides (LAPs) comprise a subclass of RiPPs that display outstanding diversity of mechanisms of action while sh...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Travin, Dmitrii Y., Watson, Zoe L., Metelev, Mikhail, Ward, Fred R., Osterman, Ilya A., Khven, Irina M., Khabibullina, Nelli F., Serebryakova, Marina, Mergaert, Peter, Polikanov, Yury S., Cate, Jamie H. D., Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783444/
https://ncbi.nlm.nih.gov/pubmed/31594941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12589-5
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