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Klebsazolicin inhibits 70S ribosome by obstruction of the peptide exit tunnel
While screening of small-molecular metabolites produced by most cultivatable microorganisms often results in rediscovery of known compounds, genome-mining programs allow to harness much greater chemical diversity and result in discovery of new molecular scaffolds. Here we report genome-guided identi...
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| 發表在: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701663/ https://ncbi.nlm.nih.gov/pubmed/28846667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2462 |
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