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Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state
The emergence of multi-drug resistant bacteria is limiting the effectiveness of commonly used antibiotics, which spurs a renewed interest in revisiting older and poorly studied drugs. Streptogramins A is a class of protein synthesis inhibitors that target the peptidyl transferase center (PTC) on the...
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| Izdano u: | Nucleic Acids Res |
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| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499580/ https://ncbi.nlm.nih.gov/pubmed/28505372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx413 |
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