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Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion

p21-activated kinases (PAKs) are serine/threonine kinases functioning as downstream effectors of the small GTPases Rac1 and Cdc42. Members of the PAK family are overexpressed in human breast cancer, but their role in mammary gland development is not fully explored. Here we examined the functional ro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rabieifar, Parisa, Zhuang, Ting, Costa, Tânia D. F., Zhao, Miao, Strömblad, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783434/
https://ncbi.nlm.nih.gov/pubmed/31594963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50819-4
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