Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion

BACKGROUND: Testosterone is a driver of prostate cancer (PC) growth via ligand-mediated activation of the androgen receptor (AR). Tumors that have escaped systemic androgen deprivation, castration resistant prostate cancers (CRPC), have measurable intratumoral levels of testosterone, suggesting that...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Kaipainen, Arja, Zhang, Ailin, da Costa, Rui M. Gil, Lucas, Jared, Marck, Brett, Matsumoto, Alvin M., Morrissey, Colm, True, Lawrence D., Mostaghel, Elahe A., Nelson, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783279/
https://ncbi.nlm.nih.gov/pubmed/31376206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23874
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