Nitric Oxide Protects PC12 Cells from Serum Deprivation-Induced Apoptosis by cGMP-Dependent Inhibition of Caspase Signaling

Although nitric oxide (NO) induces neuronal cell death under some conditions, it also can prevent apoptosis resulting from growth factor withdrawal. We investigated the molecular mechanism by which NO protects undifferentiated and differentiated PC12 cells from trophic factor deprivation-induced apo...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Kim, Young-Myeong, Chung, Hun-Taeg, Kim, Sung-Soo, Han, Jeong-A, Yoo, Yeong-Min, Kim, Ki-Mo, Lee, Gwang-Hoon, Yun, Hye-Young, Green, Angela, Li, Jianrong, Simmons, Richard L., Billiar, Timothy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782848/
https://ncbi.nlm.nih.gov/pubmed/10436031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-16-06740.1999
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