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RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease
In this study we used an in situ approach to identify the oxidized nucleosides 8-hydroxydeoxyguanosine (8OHdG) and 8-hydroxyguanosine (8OHG), markers of oxidative damage to DNA and RNA, respectively, in cases of Alzheimer’s disease (AD). The goal was to determine whether nuclear and mitochondrial DN...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782583/ https://ncbi.nlm.nih.gov/pubmed/10066249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-06-01959.1999 |
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